Friday, December 14, 2007

Esomeprazole for NSAID ulcers.

Nottingham, UK - Two AstraZeneca-funded studies have found that esomeprazole magnesium (Nexium) cuts gastrointestinal (GI) symptoms in patients on chronic NSAID therapy, including coxibs. "People who use NSAIDs regularly are at high risk for upper-GI disturbances, including dyspepsia, abdominal pain, and heartburn," Dr King James Scheiman (University of Card game, Ann Arbor) said in a company-issued furniture liberation. "Although reaction the NSAID medication or discontinuing therapy might ease GI symptoms, these alterations often are not an choice for many patients because of the chronic existence of their underlying healthiness. These two trials demonstrate that Nexium was effective in reduction upper-GI symptoms of patients on chronic NSAID therapy."
These two trials demonstrate that Nexium was effective in reduction amphetamine-GI symptoms of patients on chronic NSAID therapy.
Led by Dr Chris Hawkey (University Medical institution, Nottingham, UK), the discipline authors, mostly employees and consultants for AstraZeneca, peak out that proton-pump inhibitors are now well recognized as valuable agents for the prevention of recurrent ulcer complications in patients using NSAIDs. In the May 2007 periodical of the American language Book of account of Gastroenterology, they write, "Other recently reported data have also shown a change in the relative frequency of ulcer alteration in patients using selective COX-2 inhibitors as well as nonselective NSAIDs if they are given esomeprazole."

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